Candida Species From Eye Infections: Drug Susceptibility, Virulence Factors, and Molecular Characterization

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Candida Species From Eye Infections: Drug Susceptibility, Virulence Factors, and Molecular Characterization.

Purpose To determine the type of Candida species in ocular infections and to investigate the relationship of antifungal susceptibility profile to virulence factors. Methods Fifty isolates of yeast-like fungi from patients with keratitis, endophthalmitis, and orbital cellulitis were identified by Vitek-2 compact system and DNA sequencing of ITS1-5.8S-ITS2 regions of the rRNA gene, followed by ...

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Introduction: Acne is a pathological disorder and a chronic inflammation in the sebaceous follicles, and one of the most popular dermatology damages that has affected millions of people worldwide. The aim of this study was to identify Candida species in patients with acne as well as determine the drug susceptibility of these species.   Materials & Methods: In this cross-sectional study, 70 cl...

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Background: Vulvovaginal candidiasis (VVC) is an important health problem caused by Candida spp. The aim of this study was molecular identification, phylogenetic analysis, and evaluation of antifungal susceptibility of non-albicans Candida isolates from VVC. Methods: Vaginal secretion samples were collected from 550 vaginitis patients at Sayyad Shirazi Medical and Educational Center of Gorgan (...

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Molecular identification and in-vitro antifungal susceptibility testing of Candida species isolated from patients with onychomycosis

Background and Purpose: Candida species are the most opportunistic fungi affecting the nails and resulting in onychomycosis. In this study, we identified and evaluated in-vitro susceptibility of the recovered isolates against fluconazole (FLC), voriconazole (VRC), and clotrimazole (CLT) using the Clinical and Laboratory Standards Institute (CLSI) M27-A3 document. Materials and Method...

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Virulence factors of Candida species.

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ژورنال

عنوان ژورنال: Investigative Opthalmology & Visual Science

سال: 2017

ISSN: 1552-5783

DOI: 10.1167/iovs.17-22003